Valentine"s Day Present Tips For Him - Jewelry You don"t want a whole lot of time and funds to make a fantastic homemade costume for Halloween. You can make a low cost and straightforward costume by rummaging in your closet and looking your neighborhood thrift shop and dollar store for costume clothes and add-ons. Your jewellery, makeup and craft supplies will also support you to create a low cost and simple costume. You"ll want to be resourceful and imaginative. Learn how to combine and match no matter what costume clothing and accessories you can locate. If you get started out early sufficient, you can also store on websites like eBay or Craigslist for low-cost costume items. If I may possibly be critical for a minute, I have a number of recommendations for presents for the elderly. debossed wristbands Yet another caveat. There are distinct scenarios within the senior ranks. Conditions can selection from currently being an independent, energetic man or woman who will get around with out support, all the way to people who are confined to a nursing residence. As a result, I"ll propose several from each and every class. Banana Clips and Pineapple Clips - These are cute hair accessories that came in various designs and colours. Banana clips are obviously banana shaped combs that is utilized to make the hair remain neatly in place. It is greatest worn for women with extended flowing hair. Though not the most standard use, you can use printed wristbands coffee mugs as flower holders! It could seem to be a bit random in a sense but coffee mugs can make for best flower holders, especially for those plants that are little and can continue to be potted. This is a fantastic way to naturally liven up your workplace. You can choose to use all sorts of plants from petite roses, ivy, violets, and many other folks! Design and style your printed wristbands mugs with all sorts of types and colours and your plants will genuinely pop. Simple. Frequently occasions simple operates nicely for a man. This might be a leather wristband with an easy face, it may possibly be a metal band with a straightforward face, or you could choose a straightforward plastic or rubber blend with a digital face. When you choose these choices you want to look for something that fits the guy who will dress in it. Before you even get started on a six-week body makeover, buy anything that you can dress in as a reminder. It could be a ring or one particular of individuals cool wristbands, anything that consistently says, "Oh yea, I need to perform on my program these days." Writing notes on mirrors in the bathroom, on the refrigerator, and in the vehicle don"t assist as much due to the fact when you leave those spots the out of sight out of mind mentality comes into play. Even a constant vibration alarm on your cell telephone every single hour on the hour will do the trick. Lego Close friends are also hugely well-known with women, and there"s a new Lego Mindstorms set out there for older youngsters who have a real interest in science. You can"t genuinely go incorrect with Lego at Christmas! If you already have a near-fitting dress with a flared skirt, you can make an inexpensive and straightforward 50s Halloween costume. Nevertheless, you may possibly also be capable to discover this type of dress really cheaply at a thrift shop. Locate a white apron, a basic belt, a modest white scarf and white gloves. Design your hair into tight curls by wearing sponge rollers overnight. Wear pearl earrings, studs or clip-ons. Tie the scarf all around your neck and make up your encounter with a tiny basis and lots of face powder with red lipstick, light eyeshadow and mascara. Dress in nude hose and substantial heeled pumps. Carry add-ons this kind of as a spatula, a rolling pin or a broom to make your 50s housewife costume total.

GV-971, the home-grown drug treating Alzheimer"s disease. [Photo provided to chinadaily.com.cn]

Chinese medicine that can improve cognition first to pass clinical trials

A homegrown drug that is the world"s first innovative therapy for treating Alzheimer"s disease in 17 years will be available to Chinese patients before the end of this year, its developers said on Sunday.

China"s National Medical Products Administration approved the market launch of the drug, GV-971, on Saturday, making it the only Alzheimer"s medicine out of more than 320 developed by pharmaceutical companies around the globe to survive clinical trials, despite the investment of hundreds of billions of US dollars over the past two decades.

Extracted from brown algae, the orally taken drug is the world"s first multi-targeting and carbohydrate-based drug for Alzheimer"s, the administration said. It can treat mild to moderate forms of the disease and improve cognition, it said.

The first production line for the drug, which will meet the needs of 2 million patients, will begin running this week. Patients will be able to buy the drug around the country from Dec 29, and more production lines will gradually be put into operation to satisfy market demand, according to Shanghai Green Valley Pharmaceutical, one of the drug"s developers.

The Chinese Academy of Sciences" Shanghai Institute of Materia Medica, which jointly developed the drug with Green Valley and Ocean University of China after 22 years of research, said there were previously five medicines with limited efficacy used to treat the disease, which was discovered a century ago.

Alzheimer"s disease, an irreversible and progressive brain disorder that slowly destroys memory, thinking ability and the capability to carry out simple tasks, affects at least 50 million people worldwide, and the number is expected to increase as populations age.

China has roughly 10 million people with Alzheimer"s, the most in the world. A phase III clinical trial of the drug involving 818 patients completed in July last year had "proven to continuously and effectively improve cognition among mild to moderate Alzheimer"s disease sufferers over a period of nine months," said Geng Meiyu, lead researcher on the drug and a researcher with SIMM.

"Addiction and serious toxicity of the therapy haven"t been identified in research so far," she said.

Scientists said the drug functions mainly by rebalancing gut microbiota, reducing neuro-inflammation and reducing cognitive impairment. Some doctors from home and abroad, including David Holtzman, chairman of the American Neurological Association, said they believe GV-971 will provide a new medical solution for patients.

Preparations are being made for the drug"s clinical trials in the United States and international multi-center research, its developers said, with initial communication with the US Food and Drug Administration already completed.

"Green Valley has established a professional team and hired world-renowned experts in this field as consultants in preparation for initiating clinical trials in the US," said Lyu Songtao, the company"s chairman. "We don"t exclude the possibility of collaborating with international research institutions to perform clinical trials in the US."

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